69 Best Engineering Startups in United States to Watch in 2024

Comprehensively mapping and reprogramming the immune system with single-cell biology and AI to power new therapeutic discoveries, accelerate drug development and improve patient outcomes

Total Raised: $313.00M

Last Funding: $18.00M (Unknown)

Machine learning platform for data scientists and engineers to help create enterprise AI.

Total Raised: $746.63M

Last Funding: $400.00M (Series E)

TenNor Therapeutics specializes in research and development of new drugs for the treatment of digestive diseases

Total Raised: $66.00M

Last Funding: $41.00M (Series E)

Cytovale is a company that develops biomarkers based on the mechanical properties of cells to identify diseases. It has applied its technology to detect sepsis.

Total Raised: $119.30M

Last Funding: $100.00M (Series D)

ZAP Surgical Systems designs and manufactures the ZAP-X® radiosurgery platform.

Total Raised: $159.00M

Last Funding: $78.00M (Series E)

InterVene is an up and coming medical device start-up company reinventing the way physicians treat severe venous disease in the legs.

Total Raised: $28.00M

Last Funding: $13.00M (Series A)

Okami Medical develops and commercializes new devices for the treatment of heart disease.

Total Raised: $39.70M

Last Funding: $32.50M (Unknown)

Centaur Labs is a medical AI platform that offers medical data labeling services.

Total Raised: $16.15M

Last Funding: $16.00M (Series B)

Cerecin, formerly Accera, is a company that looks to develop therapeutic drugs for neurodegenerative diseases.

Total Raised: $59.50M

Last Funding: $11.00M (Series D)

SparingVision is a retinal Gene Therapy Treatments founded by Jose alain sahel.

Total Raised: $52.81M

Last Funding: $52.81M (Series A)

Immatics Biotechnologies is a biopharmaceutical company focused on the discovery and development of immunotherapy of cancer.

Total Raised: $180.09M

Last Funding: $58.00M (Series E)

Translate Bio is a clinical-stage mRNA therapeutics company developing medicines to treat diseases caused by protein or gene dysfunction and vaccines against infectious disease pathogens.

Total Raised: $183.00M

Last Funding: $47.50M (Unknown)

A healthcare technology company offering a cloud-based molecular profiling platform.

Total Raised: $250.80M

Last Funding: $250.80M (Series A)

NantHealth is a Culver City, California-based company providing an evidence-based platform for healthcare diagnostics.

Total Raised: $100.00M

Last Funding: $75.00M (Unknown)

SOPHiA GENETICS is a healthcare technology company and developer of SOPHiA Artificial Intelligence for clinical genomics.

Total Raised: $110.00M

Last Funding: $110.00M (Unknown)

Immunocore Limited is a biotechnology research company based in Abingdon, Oxfordshire focused on developing therapies for the treatment of cancer.

Total Raised: $75.00M

Last Funding: $75.00M (Series C)

Theseus Pharmaceuticals is a kinase Inhibitors founded by Wei-Sheng Huang.

Total Raised: $100.00M

Last Funding: $100.00M (Series B)

Product management system aiding organizations in getting products to market faster.

Total Raised: $45.00M

Last Funding: $45.00M (Unknown)

Lysogene is a company by Karen Aiach.

Total Raised: $16.50M

Last Funding: $16.50M (Series A)

Carl Zeiss Meditec is a medical Devices founded in 2002 by Carl Zeiss.

Total Raised: $1.90M

Last Funding: $1.90M (Seed)

codeSpark is a company founded in 2014.

Total Raised: $2.50M

Last Funding: $2.50M (Seed)

A software solutions company providing bioinformatics solutions to life science and other sector

Total Raised: $2.26M

Last Funding: $0.74M (Unknown)

Indemnis UAV Recovery Systems is an Anchorage, Alaska-based company developing safety solutions to the commercial UAV community.

Total Raised: $2.00M

Last Funding: $2.00M (Seed)

Asklepios Biopharmaceutical is a company in North Carolina.

Total Raised: $1.60M

Last Funding: $1.60M (Unknown)

Vizgen is a biotech company that develops solutions for next-generation spatially resolved, single-cell transcriptomics.

Last Funding: $0.00M (Series D)

Magnolia Neurosciences is a Seattle-based company founded in 2018.

Locanabio is a San Diego, California-based biotechnology company developing RNA-targeting gene therapies.

Guardant Health is a Redwood City, California-based biotechnology company developing precision oncology treatments.

Chai Biotechnologies (also known as Chai and Chai Bio) is a biotechnology company building real-time PCR, qPCR and devices that detect pathogens, speciate meat and genotype DNA.

Engine Biosciences is a San Francisco-based AI company that is focused on drugs development.

Rgenix is a cancer treatment company founded in 2010 by Shahram Seyedin-Noor, Saeed Tavazoie, Masoud Tavazoie and Sohail Tavazoie.

Tmunity Therapeutics is a biotechnology company developing t-cell immunotherapies for the treatment of human diseases.

Passage Bio, Inc is a Philadelphia-based biotechnology company developing genetics-based medicines.

Aro Biotherapeutics is a protein Scaffolds founded in 2018.

Lava Therapeutics is a biotechnology research company developing bispecific gamma-delta T cell engaging (bsTCE) antibodies to fight cancer.

Tempus, a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

Suvoda is a clinical Trial Software founded in 2012.

Allay Therapeutics is a multi-week Localized Pain Management.

ApoGen Biotechnologies is focused on the development of new class of therapeutics targeting drivers of cancer genomic mutation.

Imvax is a clinical-stage biotechnology company focused on the development of patient-specific vaccines and immunotherapy strategies for the treatment of malignant gliomas and other cancers with unmet medical needs.

Covance is Now Labcorp Drug DevelopmentOur name has changed but our mission remains the same—to continue bringing you advanced drug, device, and diagnostic breakthroughs.

Namocell is a manufacturer of single-cell sorting and dispensing platforms for single-cell research and therapeutics development.

Schrodinger is a New York-based company providing software solutions and services for life sciences and materials research.

Medable's offers a healthcare application that provides patient-generated data for researchers, health startups, pharmaceuticals and universities.

GenMark Diagnostics is a Carlsbad, California-based medical diagnostics company founded in 2010 and developing point-of-care diagnostic software and instruments.

Design, integrate, and automate document workflows using a single platform.

Iovance Biotherapeutics is a late-stage oncology company with the potential to bring the first novel autologous T cell therapy to the market for solid tumors in patients with significant unmet needs.

Insilico Medicine is a drug discovery, artificial intelligence company that looks to treat cancer and age related diseases

A bioinformatics company in San Francisco building data collection methods and databases that will enable machine learning algorithms in healthcare. It was founded in 2018.

A clinical stage biopharmaceutical company in R & D and the industrialization of innovative drugs and high-end biological similar drugs. Clover Biopharmaceuticals is focused on tumor treatment and autoimmune diseases.

Insightec is a Tirat Carmel-based company developing and manufacturing MR-guided focused ultrasound devices for image-guided acoustic surgery.

A software-as-a-service technology company with a focus on robotic solutions for laboratories. It was founded in 2019 and is located in Menlo Park, California.

A biopharmaceutical company developing protein therapeutics

Vaxxinity, Inc. is a Dallas, Texas-based biotechnology company focused on the development and commercialization of prophylactic and therapeutic vaccines to combat chronic disorders and infectious diseases.

Orchard Therapeutics is a biotechnology company developing gene therapies for rare diseases.

Tasso is a Seattle-based manufacturer and supplier of blood-based diagnostic tools.

Metagenomi is a Gene-Edited Microbial Treatments.

Artificial Intelligence company

Akouos is a Brookline, Massachusetts-based biotechnology company developing precision genetics-based medicines founded in 2016 by Emmanuel Simons.

DNAnexus is a Mountain View, California-based cloud computing and bioinformatics company.

Upside Foods is a San Francisco-based company making cultured meat products. The company was founded by Uma Valeti, Nicholas Genovese, and Will Clem.

Verge Genomics is a company focused on the discovery and development of drugs for the treatment of neurodegenerative diseases with the use of machine learning and computational genomics.

Carisma Therapeutics is a biotechnology company founded in 2016 to bring the potheyr of adoptive cellular immunotherapy to solid tumor patients through a novel platform using chimeric antigen receptor macrophages (CARMA).

Syapse is a clinical & Molecular Data Analytics founded in 2008 by Glenn Winokur, Jonathan Hirsch and Tony Loeser.

Wild Type is a San Francisco based company producing meat products like salmon using cellular agriculture lab techniques.

Achates Power is a San Diego-based company founded in 2004.

Great Basin Scientific provides molecular diagnostics services.

Clinical Research

NuProbe is a Cambridge, Massachusetts-based molecular diagnostics company focused on accelerating precision diagnostics.